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CRF Antagonist
White to off-white lyophilized solid. PROTECT FROM MOISTURE. A stable analog of porcine motilin with full biological activity. Acts as a potent antagonist of CRF receptors. Blocks stress-induced hypophagia and weight loss. Purity: ³97% by HPLC. Sold on the basis of peptide content. CAS 99658-03-4.
H-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2
Ref.: Samgin, G.N., et al. 1999. Am. J. Physiol.276, R1461; Moody, T.W., et al. 1994. Peptides15, 281; Milton, N.G., et al. 1993. J. Physiol.465, 415; River, J., et al. 1984. Science224, 889.
Synonyms: CRF Antagonist
C~1~6~6H~2~7~4N~4~6O~5~3S~2
CAS: 99658-03-4
MDL: not available
Molecular Weight: 3826.4
Merck Index: not available
| Description: | A-CORTICOTROPIN-RELEASING FACT |
| Unit: | Each (1 MG) |