EMD ADP-HPD Dihydrate Ammonium 118415-1SET w/ Free Shipping and Handling

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Adenosine 5′-diphosphate (Hydroxymethyl)pyrrolidinediol, NH₄

White lyophilized solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC₅₀ = 120 nM). Does not affect the activities of either poly(ADP-ribose) polymerase (PARP) or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1 mM concentration. Also acts as an inhibitor of NAD glycohydrolase (IC₅₀ = 260 mM) from Bungarus fasciatus venom. Purity: ³95% by HPLC. Note: 1 set = 5 x 60 mg

Ref.: Vispe, S., et al. 2000. Proc. Natl. Acad. Sci. USA97, 9886; Slama, J.T., et al. 1995. J. Med. Chem.38, 389; Slama, J.T., et al. 1995. J. Med. Chem.38, 4332.

Synonyms: Adenosine 5′-diphosphate (Hydroxymethyl)pyrrolidinediol, NH₄

C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O

CAS: not available

MDL: MFCD03452657

Molecular Weight: 595.4

Merck Index: not available

Specifications for EMD ADP-HPD Dihydrate Ammonium 118415-1SET:

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