EMD Cycloheximide 100MG 239764-100MG w/ Free Shipping

EMD Cycloheximide 100MG 239764-100MG is one of the many quality laboratory and scientific products we have to offer at very competitive pricing. EMD Cycloheximide 100MG 239764-100MG / 80059-086 is part of a wide selection of EMD Molecular biology and specialized reagents. Combining excellent quality with an affordable price, the EMD Cycloheximide 100MG 239764-100MG / 80059-086 can meet your scientific research needs while still offering a good value for a budget conscious end user. If you have any questions about any of our Molecular biology and specialized reagents please do not hesitate to contact our customer service for further guidance.

White to yellow solid.Antifungal antibiotic that does not affect several species of pathogenic bacteria even at 100µg/mL. Inhibits protein synthesis in eukaryotes but not in prokaryotes. Interacts directly with the translocase enzyme, interfering with the translocation step. Inhibits cell-free protein synthesis in eukaryotes. Triggers apoptosis in HL-60 cells, T cell hybridomas, Burkitt's lymphoma cells, and a variety of other cell types including rodent macrophages. However, it inhibits DNA cleavage in rat thymocytes treated with thapsigargin (80055-474), methyl-prednisolone, and lonomycin. Rapidly destroyed in alkaline solutions.

Purity: >=95% by assay.Soluble in trichloromethane, ethanol, and methanol.

FW: 281.3

CAS: 66-81-9

Merck Index: 12, 2797

Storage and Handling: Shipped as hazardous. Store at room temperature, 20°C (68°F).

Warning: Highly toxic. LD₅₀ of <=50mg/kg. May be carcinogenic/teratogenic.

Literature References: Lu, Q., et al. 1996. Arch. Biochem. Biophys. 334, 175; Chow, S.C., et al. 1995. Exp. Cell. Res. 216, 149; Cotter, T.G., et al. 1992. Anticancer Res. 12, 773.

Specifications for EMD Cycloheximide 100MG 239764-100MG:

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