EMD Inhibitor B-SECRETASE Ii 1MG 565749-1MG w/ Free Shipping

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N-Benzyloxycarbonyl-Val-Leu-leucinal

Z-VLL-CHO

White lyophilized solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent, cell-permeable, and reversible inhibitor of b-secretase. Corresponds to the b-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Ab_total (IC₅₀ = 700 nM) and Ab_1-42 (IC₅₀ = 2.5 mM) in Chinese hamster ovary (CHO) cells stable transfected with wild-type APP751. Purity: ³95% by HPLC.

Ref.: Abbenante, G., et al. 2000. Biochem. Biophys. Res. Commun.268, 133.

Synonyms: N-Benzyloxycarbonyl-Val-Leu-leucinal, Z-VLL-CHO

C₂₅H₃₉N₃o₅

CAS: not available

MDL: MFCD03453567

Molecular Weight: 461.6

Merck Index: not available

Specifications for EMD Inhibitor B-SECRETASE Ii 1MG 565749-1MG:

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