
Code: EM-94I-559396-500UG
MPN: 559396-500UG
EMD Inhibitor Sb 220025 500UG 559396-500UG is one of the many quality laboratory and scientific products we have to offer at very competitive pricing. EMD Inhibitor Sb 220025 500UG 559396-500UG / 80054-382 is part of a wide selection of EMD Molecular biology and specialized reagents. Combining excellent quality with an affordable price, the EMD Inhibitor Sb 220025 500UG 559396-500UG / 80054-382 can meet your scientific research needs while still offering a good value for a budget conscious end user. If you have any questions about any of our Molecular biology and specialized reagents please do not hesitate to contact our customer service for further guidance.![]()
5-(2-Amino-4-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinlyl)imidazole
Beige solid. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A potent and specific inhibitor of human p38 mitogen-activated protein kinase (MAPK; IC50 = 60 nM). Exhibits over 2000-fold greater selectivity for p38 MAPK over ERK (p42/p44 MAP kinase), 500-fold over PKA, 50-fold over PKC, and >1000-fold over EGFR. Also acts as a potent inhibitor of angiogenesis and as an inhibitor of TNF-a production. Purity: ³95% by HPLC.
Ref.: Jackson, J.R., et al. 1998. J. Pharmacol. Exp. Ther.284, 687; Wang, Z., et al. 1998. Structure6, 1117.
Synonyms: 5-(2-Amino-4-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinlyl)imidazole
C18H19FN6
CAS: not available
MDL: MFCD02179213
Molecular Weight: 338.4
Merck Index: not available
| Description: | INHIBITOR SB 220025 500UG |
| Unit: | Each (500 UG) |