EMD Peptide BCL-2 Binding CELL-PE 197220-1MG w/ Free Shipping and Handling

EMD Peptide BCL-2 Binding CELL-PE 197220-1MG is one of the many quality laboratory and scientific products we have to offer at very competitive pricing. EMD Peptide BCL-2 Binding CELL-PE 197220-1MG / 80512-344 is part of a wide selection of EMD Chemistry quality controls or calibrators or standards. Combining excellent quality with an affordable price, the EMD Peptide BCL-2 Binding CELL-PE 197220-1MG / 80512-344 can meet your scientific research needs while still offering a good value for a budget conscious end user. If you have any questions about any of our Chemistry quality controls or calibrators or standards please do not hesitate to contact our customer service for further guidance.

cpm-1285

Decanoyl-KN¹⁴⁰LWAAQRYGRELRRMSDEFEGSFKGL¹⁶⁵-OH

Off-white lyophilized solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A cell-permeable peptide that binds to Bcl-2 with high binding potency (~130 nM) and induces apoptosis. Displays antitumor activities in cells overexpressing Bcl-2 with no apparent effect in normal peripheral lymphocytes. The peptide is derived from the BH3 domain (residues 140 - 165, a "death domain") of Bad and is modified to be cell permeant by attaching a decanoyl moiety at the N-terminus. Purity: ³95% by HPLC.Supplied as a trifluoracetate salt.

CH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH

Ref.: Wang, J-L., et al. 2000. Cancer Res.60, 1498; Kelekar, A., et al. 1997. Mol. Cell. Biol.17, 7040.

Synonyms: Decanoyl-KN¹⁴⁰LWAAQRYGRELRRMSDEFEGSFKGL¹⁶⁵-OH, cpm-1285

C₁₅₃H₂₄₀N₄₄O₄₂S

CAS: not available

MDL: MFCD03456163

Molecular Weight: 3399.9

Merck Index: not available

Specifications for EMD Peptide BCL-2 Binding CELL-PE 197220-1MG:

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