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3-Hexadecanoyl-5-hydroxymethyl-tetronic Acid
Pale yellow solid. PROTECT FROM LIGHT. A specific non-cell-permeable inhibitor of protein tyrosine phosphatase. Inhibits dephosphorylation activity of CD45 (IC50 = 54 mM) and VHR (vaccinia H1-related; IC50 = 2.0 mM) in vitro. Also inhibits cell cycle progression of Ball-1 cells at the G1/S transition and enhances ATP-induced long-term potentiation in guinea-pig hippocampal CA1 neurons. Purity: ³98% by TLC.
Ref.: Fujii, S., et al. 1995. Neurosci. Lett.187, 130; Fujii, S., et al. 1995. Neurosci. Lett.187, 133; Hamaguchi, T., et al. 1995. FEBS Lett.372, 54.
Synonyms: 3-Hexadecanoyl-5-hydroxymethyl-tetronic Acid
CAS: not available
MDL: MFCD00942285
Molecular Weight: 368.5
Merck Index: not available
| Description: | RK-682 STREPTOMYCES S 200UG |
| Unit: | Each (200 UG) |