EMD SMAC-N7 PEPTIDE-5MG 567370-5MG w/ Free S&H

EMD SMAC-N7 PEPTIDE-5MG 567370-5MG is one of the many quality laboratory and scientific products we have to offer at very competitive pricing. EMD SMAC-N7 PEPTIDE-5MG 567370-5MG / 80512-666 is part of a wide selection of EMD Chemistry quality controls or calibrators or standards. Combining excellent quality with an affordable price, the EMD SMAC-N7 PEPTIDE-5MG 567370-5MG / 80512-666 can meet your scientific research needs while still offering a good value for a budget conscious end user. If you have any questions about any of our Chemistry quality controls or calibrators or standards please do not hesitate to contact our customer service for further guidance.

H-AVPIAQK-OH

White lyophilized solid. PACKAGED UNDER INERT GAS. A peptide that contains the N-terminal seven residues of Smac (Second Mitochondria-derived Activator of Caspases, also known as DIABLO) and promotes procaspase-3 activation at around 10 mM. Reported to bind to the BIR2 and BIR3 (baculovirus IAP repeat) domains of XIAP (X-liked inhibitor of apoptosis proteins) with a K_d ~800 nM. Promotes the catalytic activity of caspase-9 in the binding to the same pocket on the surface of XIAP. Purity: ³95% by HPLC.Supplied as a trifluoroacetate salt.

H-Ala-Val-Pro-Ile-Ala-Gln-Lys-OH

Ref.: Srinivasula, S.M., et al. 2001. Nature410, 112; Chai, J., et al. 2000. Nature406, 855; Liu, Z., et al. 2000. Nature408, 1004; Srinivasula, S.M., et al. 2000. J. Biol. Chem.275, 36152.

Synonyms: H-AVPIAQK-OH

C₃₃H₅₉N₉O₉

CAS: not available

MDL: MFCD03458534

Molecular Weight: 725.9

Merck Index: not available

Specifications for EMD SMAC-N7 PEPTIDE-5MG 567370-5MG:

(Please note that the description and stock photo may not correspond to the specific model listed above)

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