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Carrier proteins are used for coupling with peptides or other haptens that are not sufficiently large or complex on their own to induce an immune response and produce antibodies. The carrier protein confers immunogenicity to the conjugated hapten, resulting in antibodies being produced against epitopes on the hapten and carrier. Carriers are chosen based on immunogenicity, solubility, and availabilty of useful functional groups. All carrier proteins are lyophilized in PBS buffer, unless otherwise stated.
Bovine serum albumin (BSA) and ovalbumin are commonly used to determine antibody yield in an ELISA analysis. Mariculture keyhole limpet hemocyanin (mcKLH) protein is widely used as a carrier protein because of its large size and many available lysine groups. Because it is derived from a mollusk, it elicits a stronger immune response than BSA or ovalbumin while minimizing cross-reactivity. SuperCarrier* immune modulator carrier protein is designed to enhance the antibody response to haptens and large proteins. It consists of a BSA with the carboxyl groups converted to primary amines to provide multiple amino groups as targets. The maleimide activated carrier proteins contain cystein peptides that have been preactivated for high sulfhydryl reactivity and stability.
| Description: | Bovine Serum Albumin in MES Buffer |
| Size: | 2 mg |
| Unit: | Each (2 MG) |