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1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid, 4-Methoxyphenyl Ester
White solid. A 4-methoxyphenyl ester derivative of the non-steroidal anti-inflammatory drug (NSAID) Indomethacin (Cat. No. 405268) that acts as a potent and selective inhibitor of COX-2 (IC50 = 40 nM) compared to COX-1 (IC50 >66 mM). Purity: ³97% by HPLC.
Ref.: Kalgutkar, A.S., et al. 2000. J. Med.Chem.43, 2860; Kalgutkar, A.S., et al. 2000. Proc. Natl Acad. Sci. USA97, 925.
Synonyms: 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid, 4-Methoxyphenyl Ester
C26H22ClNO5
CAS: not available
MDL: MFCD03452681
Molecular Weight: 463.9
Merck Index: not available
| Description: | INDOMETHACIN ESTER 4-METHOXY |
| Unit: | Each (5 MG) |