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N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-benzyloxycarbonylpiperazine-2-carboxamide
White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A piperazine-based potent inhibitor of MMP-9 (IC50 = 1.9 nM) and MMP-13 (IC50 = 1.3 nM). Inhibits MMP-1 and MMP-3 at higher concentrations (IC50 = 24 nM and 18 nM, respectively). Also acts as a weak inhibitor of MMP-7 (IC50 = 230 nM). Purity: ³95% by HPLC.
Ref.: Cheng, M., et al. 2000. J. Med. Chem. 43, 369.
Synonyms: N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-benzyloxycarbonylpiperazine-2-carboxamide
C20H23N3O7S
CAS: not available
MDL: MFCD03453559
Molecular Weight: 449.5
Merck Index: not available
| Description: | INHIBITOR MMP-9/MMP-13 II-1MG |
| Unit: | Each (1 MG) |